Location: DIBIT1 A1, Floor 3
Joint unit leader, Experimental Immunology Unit
Giulia Casorati obtained a degree in Biological Science (summa cum laude) at the university of Torino in 1987 with Prof Nicola Migone, working on the genetic structure of TCR and immunoglobulin variable regions. She obtained a PhD in Human Genetics at the university of Torino in 1992. Between 1988-91, she joined Klaus Karjalainen lab at the Basel Institute for Immunology, where she studied the structure of the TCRs ab and gd and contributed to the identification of human invariant NKT cells together with Paolo Dellabona and Antonio Lanzavecchia.
Since 1992 she joint-directs with Paolo Dellabona the Experimental Immunology Unit at IRCCS Ospedale San Raffaele in Milano.
She has published more than 140 papers on peer-reviewed journals with a total h-index = 46 (ISI Web of Science April 2018). In 2010 she was listed among the 100 more cited Italian scientists.
She is member of the Italian Society of immunology and clinical Immunology and allergology (SIICA), of the Italian Network for Tumor Biotherapy (NIBIT) (since 2009) and of the Association for Cancer Immunotherapy (CIMT) (since 2011).
Since at IRCCS Ospedale San Raffaele, Giulia Casorati has been investigating fundamental mechanisms and translational aspects of the T cell immune response in cancer, with particular emphasis on CD1-restricted lipid-specific T cells. She has been interested on dissecting the development and function of human and murine invariant NKT cells both in transgenic mouse models generated in the laboratory, or in physiologic and pathologic human contexts. More recently she focused her interests to study the lipid antigen-specific CD1 restricted T cell response in leukaemia patients and designed new adoptive immunotherapy protocols to target leukemia cells.