Translational Genetics

Arcangela De Nicolo

Arcangela De Nicolo

Location: DIBIT2 A3, Floor 3

Area coordinator, Translational Genetics

Arcangela De Nicolo received her M.D. cum laude from the University of Bari, her Ph.D. in Oncology and Surgical Oncology from the University of Padua, and her 2nd level Master degree in Cancer Genetics from the University of Pavia. With a primary research focus on hereditary and sporadic breast cancer, Arcangela worked for about ten years in Boston, where she trained as a Research Fellow in Genetics and then held a joint Faculty academic appointment at the Dana-Farber Cancer Institute, Harvard Medical School, and Brigham and Women’s Hospital. Back in Italy, Arcangela joined the Veneto Institute of Oncology IRCCS in Padua as an Investigator and then Head of program section and the University of Padua as an Adjunct Faculty.


Acquainted with both clinical and research settings, Arcangela designs and/or coordinates interdisciplinary translational studies on (breast/ovarian) cancer predisposition ultimately aimed at informed clinical choices and patient-tailored cancer prevention and care. She maintains collaborations with research groups in the United States, Australia, Singapore, and several European countries and is actively involved in national and international oncology networks. Arcangela currently serves as Steering Committee member and Clinical Working Group Chair in the Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) international consortium, focusing on classification and reporting of sequence variants in BRCA1 and BRCA2 and other breast cancer susceptibility genes. Under the EU-funded iPAAC Joint Action umbrella, she started collaborating with the Istituto Superiore di Sanità to develop e-learning modules on cancer genetics and genome medicine for health care providers.


Arcangela recently joined the Center for Omics Sciences at IRCCS Ospedale San Raffaele, where she coordinates the Translational Genetics research area and contributes to a number of EU initiatives and projects, including CAN.HEAL and IDEA4RC. As a physician scientist, she plays a bridging role, liaising with clinicians, geneticists, and surgeons.