Age related diseases

Enrico Milan

Enrico Milan

Location: DIBIT1 A2, Floor 4, Room 23b

Postdoc fellow, Age related diseases Unit

Enrico obtained his master degree in Biotechnology at Università Vita-Salute San Raffaele, after an internship in the Biomolecular Mass Spectrometry Lab directed by Dr. Angela Bachi in 2009. During this experience he specialized himself in proteomics and he identified serum biomarkers able to predict patient response to EGFR inhibitor in non-small cell lung cancer (Milan et al., 2012).

In 2014, he received a PhD in Molecular Medicine at Università Vita- Salute San Raffaele in the lab of Dr. Simone Cenci investigating the role of autophagy in multiple myeloma (Milan et al. 2015). During these years he characterized the functions of the autophagic receptor of ubiquitinated proteins p62/SQSTM1 in multiple myeloma through an extensive and unbiased proteomic analysis of its interactors.

In 2015, he was visiting postdoctoral fellow in Prof. Jorge Moscat Lab at Sanford Burnham Prebys Medical Discovery Center, La Jolla CA.

He was awarded by international funding agencies with the Multiple Myeloma Research Foundation (MMRF) Junior Research Award 2016 and the International Myeloma Foundation (IMF) Brian D. Novis Research grant 2019. 

As principal investigator, he characterized the biological role and the related molecular circuits of multiple myeloma tumor suppressor FAM46C in regulating antibody secretion (Fucci et al., 2020).

This opened new lines of research focused on investigating new molecular pathway impacting on plasma cell and multiple myeloma proteostasis, antibody production and drug sensitivity.

His research activity is actually supported by Fondazione Cariplo (Ricerca Biomedica Condotta da Giovani Ricercatori) e Ministero della Sanità (Ricerca Giovani Ricercatori 2018 and 2019).