The primary goal of the Center for Omics Sciences at the IRCCS Ospedale San Raffaele (COSR) is to provide to the scientific and clinical community technologies, approaches and instruments to understand the role of the genome on diseases development, diagnosis and cure. The center promotes multi-omics research integrated with translational medicine, to shed light into disease onset mechanisms, propose new ad-hoc therapies and improve patients’ assistance.
The COSR is organized in 4 research areas, i.e. genomics, bioinformatics, innovation and human health genomics. It includes 2 research units, i.e. Proteome Biochemistry and Genomics for the diagnosis of human pathologies, and the core facility ProMeFa. It is located in the DIBIT2 buildings and counts more than 40 scientists with a large variety of expertise and backgrounds. It is characterized by an extremely interdisciplinary environment, aimed to provide scientific excellence and innovation on next-generation sequencing techniques, proteomic and metabolomic services, and bioinformatics analysis.
The Center already collaborates with many clinicians, research groups and institutes in Italy and abroad, and has been involved in over a thousand of projects.
The COSR supports and initiates novel, interdisciplinary research, projecting IRCCS Ospedale San Raffaele towards tackling disease through-omics driven translational approaches. The Center acts as a catalyst for innovative research projects by complementing existing research lines across the Institute with high throughput technologies, quantitative methods, and advanced data integration techniques.
The COSR works with clinicians from all the clinical areas and is involved in several projects aimed to study cancer genomics and genetic diseases.
The main research activities are:
- Human Health Genomics aimed to develop new diagnostic, predictive and therapeutic approaches;
- Transcriptome studies, to understand the mechanism of gene regulation and pathways involved in various physiological and pathological phenotypes;
- Epigenomics studies to find out the role of the environment in the onset of several diseases;
- Multi-omics studies integrating different types of analysis;
- Development of new bioinformatics tools.
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The center serves as a nexus for integrating multi-omics research with translational medicine. COSR advances scientific progress by helping researchers and clinicians generate, manage, and understand genomics data, through sequencing, bioinformatics analysis, proteomics and metabolomics services, interpretive collaborations and training.
The Center offers Next Generation Sequencing (NGS), Bioinformatics Analysis, Proteomics and Metabolomics services, interpretive collaborations and training. For further info and receiving a quotation connect with us writing at firstname.lastname@example.org
Head Proteome Biochemistry Unit
Facility manager, Promifa
Research collaborator, Promifa
Head, Genomics for the diagnosis of human pathologies Unit
Innovation Lab Coordinator
Human Health Genomics Coordinator
Human Health Genomics Coordinator
Simona Baghai Sain
Chiara Di Resta
Elvira Smeralda Famulari
Jose Manuel Garcia Manteiga
Senior technician, Promifa
Giulia Maria Scotti
Anna Sofia Tascini
We are looking for expert and strongly motivated scientists with a solid background in cell biology techniques, flow cytometry and next generation sequencing
We are looking for an enthusiastic bioinformatician to join the Center for Omics Sciences (COSR) and Luca Vago’s Immunogenetics, Leukemia Genomics and Immunobiology Unit