
Centers
Omics Sciences

The primary goal of the Center for Omics Sciences at the IRCCS Ospedale San Raffaele (COSR) is to provide to the scientific and clinical community technologies, approaches and instruments to understand the role of the genome, proteome and metabolome on diseases development, diagnosis and cure. The center promotes multi-omics research integrated with translational medicine, to shed light into disease onset mechanisms, propose new ad-hoc therapies and improve patients’ assistance.
Research activity
The COSR supports and initiates novel, interdisciplinary research, projecting IRCCS Ospedale San Raffaele towards tackling disease through-omics driven translational approaches. The Center acts as a catalyst for innovative research projects by complementing existing research lines across the Institute with high throughput technologies, quantitative methods, and advanced data integration techniques.
The main research activities are:
- Human Health Genomics aimed to develop new diagnostic, predictive and therapeutic approaches;
- Transcriptome studies, to understand the mechanism of gene regulation and pathways involved in various physiological and pathological phenotypes;
- Epigenomics studies to find out the role of the environment in the onset of several diseases;
- Proteomics studies, to describe and understand biological processes at protein level;
- Metabolomics studies, to identify metabolic alterations characterizing and affecting physiological and pathological contexts;
- Multi-omics studies integrating different types of analysis;
- Development of new bioinformatics tools.
Organization
The COSR is organized in 7 research areas, i.e. genomics, bioinformatics, innovation lab, human health genomics, immunogenomics lab, proteomics and metabolomics. It includes 2 research units, i.e. Proteome Biochemistry and Genomics for the Diagnosis of Human Pathologies. Multi-omics approaches are also provided as service through the activity of core facilities. It is located in the DIBIT2 buildings and counts more than 50 scientists with a large variety of expertise and backgrounds. It is characterized by an extremely interdisciplinary environment, aimed at providing scientific excellence and innovation on next-generation sequencing techniques, proteomic and metabolomic studies, as well as bioinformatics analyses.
The Center already collaborates with many clinicians, research groups and institutes in Italy and abroad, and has been involved in over a thousand of projects.
Connect with us
The center serves as a nexus for integrating multi-omics research with translational medicine. COSR advances scientific progress by helping researchers and clinicians to generate, manage, and understand genomics data, through sequencing, bioinformatics analysis, proteomics and metabolomics services, interpretive collaborations and training.
The Center for Omics Sciences is creating a series of very short movies with the goal of circulating essentials of multi-omics culture.
Here the list of the available videos on YouTube:
- COShoRt movie: RNAseq
- COShoRt movie: SingleCell Sequencing
We really hope you will enjoy these videos!
If you wish to share your feedback or suggest topics for future movie drop an email at info.cosr@hsr.it

Human Health Genomics
Silvia Bonfiglio
Gabriele Bucci

Proteomics
Annapaola Andolfo

Metabolomics
Annapaola Andolfo
The Center offers Next Generation Sequencing (NGS), Bioinformatics Analysis, Proteomics and Metabolomics services, interpretive collaborations and training. For further info and receiving a quotation connect with us writing at order.cosr@hsr.it.
One position for bioinformatician is available in the Genomics of the diagnosis of human pathologies Unit, headed by Paola Carrera
We are looking for a young web developer to join our center of translational genomics and bioinformatics
Massimo Alessio
Head of Proteome Biochemistry
Annapaola Andolfo
Manager, ProMeFa
Silvia Bonfiglio
Human Health Genomics Coordinator
Gabriele Bucci
Human Health Genomics Coordinator
Francesca Giannese
Innovation Lab Coordinator
Dejan Lazarevic
Genomics Coordinator
Marco Morelli
Bioinformatics Coordinator
Marco Punta
Area Coordinator, Immunogenomics Lab
Chiara Balestrieri
Researcher, Immunogenomics Lab
Edoardo Bellini
Computational biologist, Bioinformatics
Eugenia Bezzecchi
Computational Biologist
Donatella Biancolini
Laboratory technician
Vito Bilello
Computational biologist, Immunogenomics Lab
Eleonora Capitolo
Laboratory technician
Nicoletta Caridi
Laboratory technician
Lucrezia Carlassara
PhD student
Paola Carrera
Senior researcher
Davide Cittaro
Researcher
Antonio Conti
Laboratory Technician
Stefano De Pretis
Computational biologist
Denise Drago
Research collaborator, ProMeFa
Claudia Felici
Researcher, Innovation Lab
Silvia Galbiati
Postdoc fellow
Valentina Giansanti
Computational Biologist
Chiara Laura
Computational biologist
Cristina Lorenzi
Collaborator
Alessandro Lussana
Computational biologist
Elvira Smeralda Famulari
Researcher
Jose Manuel Garcia Manteiga
Computational biologist
Valeria Mannella
Research collaborator
Silvia Macorano
Administrative Coordinator
Cinzia Magagnotti
Senior technician, ProMeFa
Corrado Masciullo
Software engineer
Aurora Maurizio
Computational biologist
Caterina Oneto
Lab technician
Raffaella Pini
Computational biologist
Paolo Provero
Researcher
Sara Raia
Postdoc fellow
Michela Riba
Computational biologist
Valeria Rossella
Researcher, Innovation Lab
Ilario Tagliaferri
Computational biologist, Bioinformatics
Cinzia Sala
Technician
Giulia Maria Scotti
Computational biologist
Fabio Simeoni
Laboratory technician
Nadia Soriani
Technician
Andrea Spitaleri
Computational biologist
Anna Sofia Tascini
Computational biologist
Martina Tedesco
PhD student
Daniela Toniolo
Researcher
Giovanna Torri
Laboratory Technician
Marynska Ulaszewska
Researcher
Alan Zanardi
Postdoc fellow
Ettore Zapparoli
Computational biologist
Andrea Zauli
System administrator