The primary goal of the Center for Omics Sciences at the IRCCS Ospedale San Raffaele (COSR) is to provide to the scientific and clinical community technologies, approaches and instruments to understand the role of the genome, proteome and metabolome on diseases development, diagnosis and cure. The center promotes multi-omics research integrated with translational medicine, to shed light into disease onset mechanisms, propose new ad-hoc therapies and improve patients’ assistance.
The COSR supports and initiates novel, interdisciplinary research, projecting IRCCS Ospedale San Raffaele towards tackling disease through-omics driven translational approaches. The Center acts as a catalyst for innovative research projects by complementing existing research lines across the Institute with high throughput technologies, quantitative methods, and advanced data integration techniques.
The main research activities are:
- Human Health Genomics aimed to develop new diagnostic, predictive and therapeutic approaches;
- Transcriptome studies, to understand the mechanism of gene regulation and pathways involved in various physiological and pathological phenotypes;
- Epigenomics studies to find out the role of the environment in the onset of several diseases;
- Proteomics studies, to describe and understand biological processes at protein level;
- Metabolomics studies, to identify metabolic alterations characterizing and affecting physiological and pathological contexts;
- Multi-omics studies integrating different types of analysis;
- Development of new bioinformatics tools.
The COSR is organized in 7 research areas, i.e. genomics, bioinformatics, innovation lab, human health genomics, immunogenomics lab, proteomics and metabolomics. It includes 2 research units, i.e. Proteome Biochemistry and Genomics for the Diagnosis of Human Pathologies. Multi-omics approaches are also provided as service through the activity of core facilities. It is located in the DIBIT2 buildings and counts more than 50 scientists with a large variety of expertise and backgrounds. It is characterized by an extremely interdisciplinary environment, aimed at providing scientific excellence and innovation on next-generation sequencing techniques, proteomic and metabolomic studies, as well as bioinformatics analyses.
The Center already collaborates with many clinicians, research groups and institutes in Italy and abroad, and has been involved in over a thousand of projects.
Connect with us
The center serves as a nexus for integrating multi-omics research with translational medicine. COSR advances scientific progress by helping researchers and clinicians to generate, manage, and understand genomics data, through sequencing, bioinformatics analysis, proteomics and metabolomics services, interpretive collaborations and training.
The Center for Omics Sciences is creating a series of very short movies with the goal of circulating essentials of multi-omics culture.
Here the list of the available videos on YouTube:
- COShoRt movie: RNAseq
- COShoRt movie: SingleCell Sequencing
- COShoRt movie: Cancer Genomics
We really hope you will enjoy these videos!
If you wish to share your feedback or suggest topics for future movie fill out this feedback form or drop an email at email@example.com
Marco J Morelli
Human Health Genomics
The Center offers Next Generation Sequencing (NGS), Bioinformatics Analysis, Proteomics and Metabolomics services, interpretive collaborations and training. For further info and receiving a quotation connect with us writing at firstname.lastname@example.org.
Experimental Biologist Position at the Innovation Lab - COSR Unit, headed by Francesca Giannese
A bioinformatician position is available at Dynamics of Immune Response Lab, in collaboration with Center for Omics Sciences
A bioinfomatician position is available at Center for Omics Sciences, headed by Giovanni Tonon
Staff scientist position is available at Center for Omics Sciences, headed by Giovanni Tonon
Head of Proteome Biochemistry
Human Health Genomics Coordinator
Innovation Lab Coordinator
Area Coordinator, Immunogenomics Lab
Researcher, Immunogenomics Lab
Computational biologist, Bioinformatics
Stefano De Pretis
Gianna Di Sario
Elvira Smeralda Famulari
Jose Manuel Garcia Manteiga
Researcher, Innovation Lab
Computational biologist, Bioinformatics
Giulia Maria Scotti
Anna Sofia Tascini