Chromatin dynamics

Samuel Zambrano


Location: DIBIT2 A2, Floor 4, Room 43

Research associate, Chromatin dynamics Unit
Associate professor, Vita-Salute San Raffaele University

After getting his degree in theoretical physics at Complutense University, Madrid (2003), Samuel Zambrano got a Ph. D in Nonlinear Dynamics and Complex Systems between Madrid (King Juan Carlos University), Italy (National Institute of Applied Optics, Florence) and USA (University of Maryland). After serving as Assistant Professor of Physics in Madrid until 2011, and interested by the potential applications of his background to life sciences, he joined San Raffaele in 2011 thanks to the SR International Postdoctoral Programme. In close collaboration with Alessandra Agresti and Marco E. Bianchi he combines live-cell imaging, automatic image analysis, microfluidics and mathematical modelling to gain insights on the role of the oscillatory dynamics of NF-κB, a transcription factor that plays a key role in inflammation and that is often de-regulated in related diseases. More recently, he aims to apply the same quantitative approaches also to understand how other transcription factors exploit dynamics to activate gene expression programs that underpin cell fate decisions and, more broadly speaking, to understand the dynamical principles of fundamental processes in cell biology.