Divisions
Donato Inverso
Donato Inverso was originally trained as pathologist at the Faculty of Veterinary Medicine, Naples, Italy. From 2011 to 2015 he completed his PhD training in basic and applied immunology at“Università Vita Salute San Raffaele”. During this time, he utilized various murine models of hepatitis B pathogenesis alongside advanced imaging techniques to investigate the interplay between HBV-specific CD8+ T cells and liver endothelial cells. His research unveiled a novel paradigm of adaptive immune surveillance influenced by processes characteristic of liver fibrosis.In 2016, he transitioned to a postdoctoral position at the Division of Vascular Oncology and Metastasis at the German Cancer Research Center (DKFZ) in Heidelberg, where he remained until 2021.Here, he delved into the intersection of vascular biology and liver pathobiology, pioneering the drafting of the first comprehensive and spatially-resolved phosphoproteome of any vascular bed. This groundbreaking work illuminated a previously overlooked phosphorylation gradient along liver blood vessels, crucial for both liver homeostasis and regeneration.
His research has been published in esteemed scientific journals, including Nature, Cell, Cancer Cells, and Nature Medicine. He has received numerous accolades for his contributions, including the ERC Consolidator Grant, the AIRC start-up grant, the FET-OPEN grant from the European Innovation Council, a Cariplo reinforcement grant, the EMBO long-term fellowship, and the "Francesco de Luca Award" from the Accademia Nazionale dei Lincei.
2015 PhD in Basic and Applied Immunology. Università Vita-Salute San Raffaele. Milan, Italy
2009 Master Degree in Veterinary Medicine (DVM). Università Federico II. Naples, Italy
2021-present Assistant professor in Pathology. Medical Faculty, Università Vita-Salute San Raffaele. Milano, Italy.
2021-present Head of the Vascular Pathobiology Unit. Immunology, Transplantation and Infectious Disease, San Raffaele Research Hospital. Milano, Italy.
2020-2021 Akademischer Mitarbeiter (Faculty). Medical Faculty Mannheim in the Heidelberg University. Mannheim, Germany.
2016-2021 Postdoctoral Fellow. Division of Vascular Oncology and Metastasis, German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ). Heidelberg, Germany.
2010-2016 PhD fellow. Dynamics of Immune Responses Unit, San Raffaele Research Institute. Milano, Italy.
2009-2010 Research Fellow. Behavioural Neuroscience Unit, CeInGe - Advanced Biotechnology S.C.R.L, Napoli, Italy.
2024 Cariplo Reinforcement Grant
2023 ERC Consolidator Grant. Vascular Control of NASH Progression (CONNASHION). 1.9 million euro, 2025-2029
2022 AIRC Sturt-Up Grant. Spatially-resolved phosphor-proteomics of HCC heterogeneity. 1 million euro, 2022-2026
2021 FET-OPEN (Horizon2020). Consortium grant IN2SIGHT. 3.5 million euro, 2022-2026
2021 "Premio Internazionale Francesco de Luca” for cancer research. Accademia Nazionale dei Lincei
2021 EMBO postdoc fellowship. Defining a paradigm for hepatocellular carcinoma cell microvascular Invasion