Diabetes research institute
Pediatric diabetes
The Pediatric diabetes Unit promotes the health and education of all chidren with diabetes (Type 1 Diabetes, Type 2 Diabetes, monogenic diabetes). Every year more than 80 new pediatric diabetes cases are diagnosed in our unit. We perform 2500/year outpatient diabetologic visits, and more than 170 day hospitals. Actually we follow more than 1000 children and adolescents with all forms of diabetes mellitus that come to the outpatient clinic. We have bed in hospital for the diagnosis or treatment of acute complications of the disease.
Research activity
We developed a lot of experience in clinical and technological research and we participate in many national and international studies. We participated to the planning and execution of the first work on artificial pancreas in preschool children PedErPan study (PEDiatric Evolution Research PANcreas).
We work in strict connection with many different Units of the Diabetes Reesearch Institute (OSR-DRI), particularly try to study the different endotypes of type 1 diabetes and developing precision medicine approach for diabetic children. Our unit promotes diabetes prediction and prevention thanks to a strict collaboration to basic and applied research (eg TrialNet Center).
Lepore G, Bonfanti R, Bozzetto L, Di Blasi V, Girelli A, Grassi G, Iafusco D, Laviola L, Rabbone I, Schiaffini R, Bruttomesso D; Italian Study Group on the Diffusion of CSII. Metabolic control and complications in Italian people with diabetes treated with continuous subcutaneous insulin infusion. Nutr Metab Cardiovasc Dis. 2018 Apr;28(4):335-342.
Marzinotto I, Liberati D, Brigatti C, Bonfanti R, Stabilini A, Monti P, Bosi E, Piemonti L, Lampasona V. Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific. Diabetologia. 2017 Sep;60(9):1834-1835.
Zucchini S, Scaramuzza AE, Bonfanti R, Buono P, Cardella F, Cauvin V, Cherubini V, Chiari G, d'Annunzio G, Frongia AP, Iafusco D, Maltoni G, Patera IP, Toni S, Tumini S, Rabbone I; Diabetes Study Group of The Italian Society For Pediatric Endocrinology And Diabetology. A Multicenter Retrospective Survey regarding Diabetic Ketoacidosis Management in Italian Children with Type 1 Diabetes. Diabetes Res. 2016;2016:5719470.
Bonfanti R, Lepore G, Bozzetto L, Corsi A, Di Blasi V, Girelli A, Grassi G, Iafusco D, Rabbone I, Schiaffini R, Laviola L, Bruttomesso D; Italian Study Group on Diffusion of CSII in Italy. Survey on the use of insulin pumps in Italy: comparison between pediatric and adult age groups (IMITA study). Acta Diabetol. 2016 Jun;53(3):403-12.
Del Favero S, Boscari F, Messori M, Rabbone I, Bonfanti R, Sabbion A, Iafusco D, Schiaffini R, Visentin R, Calore R, Moncada YL, Galasso S, Galderisi A, Vallone V, Di Palma F, Losiouk E, Lanzola G, Tinti D, Rigamonti A, Marigliano M, Zanfardino A, Rapini N, Avogaro A, Chernavvsky D, Magni L, Cobelli C, Bruttomesso D. Randomized Summer Camp Crossover Trial in 5- to 9-Year-Old Children: Outpatient Wearable Artificial Pancreas Is Feasible and Safe. Diabetes Care. 2016 Jul;39(7):1180-5
Troncone A, Bonfanti R, Iafusco D, Rabbone I, Sabbion A, Schiaffini R, Galderisi A, Marigliano M, Rapini N, Rigamonti A, Tinti D, Vallone V, Zanfardino A, Boscari F, Del Favero S, Galasso S, Lanzola G, Messori M, Di Palma F, Visentin R, Calore R, Leal Y, Magni L, Losiouk E, Chernavvsky D, Quaglini S, Cobelli C, Bruttomesso D. Evaluating the Experience of Children With Type 1 Diabetes and Their Parents Taking Part in an Artificial Pancreas Clinical Trial Over Multiple Days in a Diabetes Camp Setting. Diabetes Care. 2016 Dec;39(12):2158-2164
Scaramuzza A, Cherubini V, Tumini S, Bonfanti R, Buono P, Cardella F, d'Annunzio G, Frongia AP, Lombardo F, Monciotti AC, Rabbone I, Schiaffini R, Toni S, Zucchini S, Frontino G, Iafusco D; Diabetes Study Group of the Italian Society for Pediatric Endocrinology and Diabetology. Recommendations for self-monitoring in pediatric diabetes: a consensus statement by the ISPED. Acta Diabetol. 2014 Apr;51(2):173-84.
Frontino G, Bonfanti R, Scaramuzza A, Rabbone I, Meschi F, Rigamonti A, Battaglino R, Favalli V, Bonura C, Sicignano S, Gioia E, Zuccotti GV, Cerutti F, Chiumello G. Sensor-augmented pump therapy in very young children with type 1 diabetes: an efficacy and feasibility observational study. Diabetes Technol Ther. 2012 Sep;14(9):762-4.
