Location: DIBIT1 A3, Floor 2, Room 57
Director, San Raffaele Telethon Institute for Gene Therapy
Group leader, Gene transfer technologies and new gene therapy strategies Unit
Group leader, Targeted cancer gene therapy Unit
Full professor, Università Vita-Salute San Raffaele
Luigi Naldini, M.D., Ph.D., is Professor of Cell and Tissue Biology and of Gene and Cell Therapy at the San Raffaele University School of Medicine and Scientific Director of the San Raffaele Telethon Institute for Gene Therapy, Milan, Italy.
He has pioneered the development and applications of lentiviral vectors for gene transfer, which have become one of the most widely used tool in biomedical research and, upon recently entering clinical testing, are providing a long sought hope of cure for several currently untreatable and otherwise deadly human diseases. Since then he has continued to investigate new strategies to overcome the major hurdles to safe and effective gene transfer, translate then into new therapeutic strategies for genetic disease and cancer, and allowed new insights into hematopoietic stem cell function, induction of immunological tolerance and tumor angiogenesis. His work also contributed to advance the use of artificial nucleases for targeted genome editing in cell and gene therapy.
He is Member of the European Molecular Biology Organization (EMBO), has been President of the European Society of Gene and Cell Therapy (ESGCT), and has been appointed as expert on the “Human Gene Editing Study” of the US National Academies of Sciences and of Medicine, and on the Italian National Committee for Biosafety, Biotechnology and Life Sciences. He was awarded a European Research Council Advanced Investigator Grant (ERC) in 2009, the Outstanding Achievement Award from the American Society of Gene and Cell Therapy (ASGCT) in 2014 and from ESGCT in 2015, an Honorary doctorate from the Vrije University, Brussel, in 2015, the Jimenez Diaz Prize in 2016, and the Beutler Prize from the American Society of Hematology (ASH) in 2017. Has published 252 scientific papers cited >33,000 times. SCOPUS Author h-index : 86
2003-2008 Co-director, San Raffaele Telethon Institute for Gene Therapy, Milan, Italy
Since 2003 Full Professor of Cell and Tissue Biology, School of Medicine, “Vita-Salute San Raffaele” University
2002-1998 Associate Professor, Torino Univ. Med. School and Director, Laboratory for Gene Transfer and Therapy, Institute for Cancer Research and Treatment, Candiolo (Torino), Italy
1998-1996 Senior Scientist and Director, Cell Genesys, Foster City, CA
1996-1994 Visiting Scientist, The Salk Institute for Biological Studies, La Jolla, CA
1996-1990 Assist. Professor, Dept. of Biomedical Sciences and Oncology, Torino University
Since 2008: Member of the Advisory Council of the American Society of Gene and Cell Therapy (ASGCT)
2005-2008 Member of the Board of Directors of the American Society of Gene and Cell Therapy (ASGCT)
Scientific Advisor on EMEA and WHO Committees for the evaluation of novel gene transfer medicines
Served on several Scientific Committees of the ASGCT, ESCGT, American Association of Cancer Research (AACR), International Society for Stem Cell Research (ISSCR), International Society of Cell Therapy (ISCT)
Associate Editor: Human Gene Therapy
Mary Ann Liebert Publisher Member of the Editorial Board: Molecular Therapy, Gene Therapy
2009 Awarded the European Research Council (ERC) Advanced Investigator Grant, which recognizes top EU scientists with an outstanding achievement track record.
2012 Awarded the Premio Sapio of the Italian Research (Health Area).
Research abstracts submitted from Luigi Naldini’s laboratory to the ASGCT and/or ESGCT Annual Meetings were selected among the top abstracts at the 1999, 2000, 2001, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011 and 2012 annual conferences.
1987-1983 PhD in Cell and Tissue Biology with P.M. Comoglio, Torino University
1983 MD, Torino University