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Cadherin 17 is a new target for the efficient and safe treatment of colorectal cancer liver metastases using CAR-T cell therapy
In a study published in Science Translational Medicine, researchers from the Innovative Immunotherapies Lab, led by Doctor Monica Casucci at IRCCS San Raffaele Hospital, have identified the adhesion molecule cadherin 17 as a novel, cancer-specific antigen to treat liver metastases in colorectal cancer using CAR-T cells.
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