Experimental oncology
Lymphoma
The unit is a dynamic and multidisciplinary component of the Department of Onco-hematology of IRCCS Ospedale San Raffaele. It includes medical doctors from Medical oncology clinical unit, Internal medicine clinical unit, Hematolgy and BMT unit, Radiotherapy and Tomotherapy unit, and the Pathology Unit.
Main target of the group is the management of patients affected by lymphoproliferative disorders according to a multidisciplinary approach. This Unit conducts and coordinates more than 30 clinical and clinico-biological trials on lymphomagenesis, prognostic factors, chemotherapy, radiation therapy, new therapeutic molecules and strategies and a strong cooperation with Units working on basic research. The medical team is on constant update on new diagnostic resources, biological knowledge and therapeutic approaches.
Ferreri AJM, Ponzoni M, Guidoboni M, Resti AG, Politi LS, Cortelazzo S, Demeter J, Zallio F, Palmas A, Muti G, Dognini GP, Pasini E, Lettini AA, Sacchetti F, De Conciliis C, Doglioni C, Dolcetti R. Bacteria-eradicating therapy with doxycycline in ocular adnexal MALT lymphoma: a multicenter prospective trial. J Natl Cancer Inst. 2006 Oct 4;98(19):1375-82.
Ferreri AJM, Dell'Oro S, Foppoli M, Bernardi M, Brandes A, Tosoni A, Montanari M, Balzarotti M, Spina M, Ilariucci F, Zaja F, Stelitano C, Bobbio F, Corazzelli G, Baldini L, Ponzoni M, Picozzi P, Cappio F, Reni M. MATILDE regimen followed by radiotherapy is an active strategy against primary CNS lymphomas. Neurology 66(9):1435-8, 2006
Guidoboni M, Ferreri AJM, Ponzoni M, Doglioni C, Dolcetti R. Infectious agents in MALT-type lymphomas: Pathogenic role and therapeutic perspectives. Clin Lymphoma Myeloma 2006 Jan;6(4):289-300.
Abrey LE, Batchelor TT, Ferreri AJM, Gospodarowicz M, Pulczynski EJ, Zucca E, Smith JR, Korfel A, Soussain C, DeAngelis LM, Neuwelt EA, O’Neill BP, Thiel E, Shenkier TN, Graus F, van den Bent M, Seymour JF, Poortmans P, Armitage JA, Cavalli F. Report of an international workshop to standardize baseline evaluation and response criteria for primary Central Nervous System lymphoma. Journal of Clinical Oncology 2005 Aug 1;23(22):5034-43.
Ferreri AJM, Ponzoni M, Guidoboni M, De Conciliis C, Giordano Resti A, Mazzi B, Lettini AA, Demeter J, Dell’Oro S, Doglioni C, Villa E, Boiocchi M, Dolcetti R. Regression of ocular adnexal lymphoma following Chlamydia psittaci-eradicating antibiotic therapy. Journal of Clinical Oncology 2005 Aug 1;23(22):5067-73.
Ferreri AJM, Campo E, Seymour J, Willemze R, Ilariucci F, Ambrosetti A, et al. Intravascular lymphoma: clinical presentation, natural history, management and prognostic factors in a series of 38 cases, with special emphasis on the “cutaneous variant”. British Journal of Haematology 2004 Oct;127(2):173-83.
Ferreri AJM, Guidoboni M, Ponzoni M, De Conciliis C, Dell’Oro S, Fleischhauer K, Caggiari L, Lettini AA, Dal Cin E, Ieri R, Freschi M, Villa E, Boiocchi M, Dolcetti R. Evidence for an association between Chlamydia psittaci and ocular adnexal lymphomas. Journal of National Cancer Institute 2004 Apr 21;96(8):586-94.
Ferreri AJM, Abrey LE, Blay JY, Borisch B, Hochman J, Neuwelt EA, Yahalom J, Zucca E, Cavalli F, Armitage J, Batchelor T. Summary statement on primary central nervous system lymphomas from the Eighth International Conference on Malignant Lymphoma, Lugano, Switzerland, June 12 to 15, 2002. Journal of Clinical Oncology 2003 Jun 15;21(12):2407-14.
Ferreri AJM, Blay JY, Reni M, Pasini F, Spina M, Ambrosetti A, Calderoni A, Rossi A, Vavassori V, Conconi A, Devizzi L, Berger F, Ponzoni M, Borisch B, Tinguely M, Cerati M, Milani M, Orvieto E, Sanchez J, Chevreau C, Dell’Oro S, Zucca E, Cavalli F. Prognostic scoring system for primary CNS lymphomas: the International Extranodal Lymphoma Study Group experience. Journal of Clinical Oncology 2003 Jan 15;21(2):266-72.
Ferreri AJM, Reni M, Pasini F, Calderoni A, Tirelli U, Pivnik A, Aondio GM, Ferrarese F, Gomez H, Ponzoni M, Borisch B, Berger F, Chassagne C, Iuzzolino P, Carbone A, Weis J, Pedrinis E, Motta T, Jouvet A, Barbui T, Cavalli F, Blay JY. A multicentre study of treatment of primary CNS lymphoma. Neurology 2002 May 28;58(10):1513-20.
