Neuroscience

Gene therapy of neurodegenerative diseases

team-item

Group Leader

Michele Simonato

MORE

The goal of Gene therapy of neurodegenerative diseases Unit is to develop innovative gene and cell therapies for neurological diseases.

Research activity

  • Development of gene therapy vectors for neurological diseases, based on herpes simplex;
  • Involvement of neurotrophic factors in the development of lesional epilepsies: identification of new therapeutic targets and development of new delivery strategies (gene therapy);
  • Neuropeptide systems (dynorphin, OFQ/N, somatostatin, NPY, bradykinin) as therapeutic targets for temporal lobe epilepsy;
  • MicroRNA as biomarkers and therapeutic targets for temporal lobe epilepsy.