Alessandro Sessa

Alessandro Sessa

Location: San Gabriele B4, 4th floor, Room 49A

Group leader, Neuroepigenetics Unit

Alessandro (Varese, 1981) received his PhD from San Raffaele Scientific Institute in Milan (I) (2012, Dr. Vania Broccoli’s laboratory), studying mechanisms underlying the cerebral cortex development. During this phase of his academic pursuit, Alessandro also enriched his scientific experience by spending six months in the laboratory of Dr. Francois Guillemot at the Medical Research Council (MRC) in London (UK). As post-doctoral fellow first and then as senior scientist within the group of Dr. Broccoli, he focused on the role of epigenetic players in the physiological development of the brain as well as the impact of disease mutations for the establishment of pathological conditions. Alessandro started as Group leader of the “Neuroepigenetic Unit” in Division of Neuroscience, Ospedale San Raffaele, in 2023.

During his career, Alessandro has made contributions to the understanding of the cellular and molecular aspects governing cerebral cortex development. His work has encompassed diverse areas, from the significance of specific cell populations to the role of cell polarity in neural stem cell differentiation, and the importance of various signaling pathways in corticogenesis. Moreover, his research endeavors have extended to the pathogenesis of neurological disorders, including microcephaly, epilepsy, and rare syndromes. Beside pure biological investigations he has contributed to methodological papers on molecular/cellular tools at the basis of the current biological research as cell reprogramming, viral delivery, and generation of synthetic epigenetic repressors.

Alessandro is contract professor at San Raffaele “Vita e Salute” University (since 2011).

He is scientific founder and consultant at Repron Therapeutics (since 2023).

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